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根据以往的群体研究和家系研究,存在一种HLA编码的T型麻风易感基因,并呈隐性遗传模式.这些研究是以假设的lr基因为基础的.但尚未获得确切的证据.通常用于体外研究lr基因表达的最可靠的方法之一是淋巴细胞转化试验(LTT).
Based on previous population studies and pedigree studies, an HLA-encoded T-linked leprosy susceptibility gene exists in a recessive genetic model based on the putative lr gene, although no definitive evidence has been available One of the most reliable methods of studying lr gene expression in vitro is the Lymphocyte Transformation Assay (LTT).