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研究难治性肺结核的治疗，对耐多药结核患者及不能耐受一线抗疗方案患者提出有效的治疗方案。采用司帕沙星为基础用药，根据患者具体情况选用下列药品的 2～ 3种：异烟肼 (INH)、利福平 (RFP)、链霉素 (SM)、乙胺丁醇 (EMB)、对氨基水杨酸钠 (PAS)，对于 25例患者采用以上方案强化治疗 6个月，每阶段均做详细观察记录。结果 25例患者有效 18例，显效 5例，进步 2例，有效率达 92％。本组 25例难治性肺结核患者经联合强化治疗初步获得了较好疗效，为临床治疗难治性结核提出新的方案。
To study the treatment of refractory pulmonary tuberculosis, the multidrug-resistant tuberculosis patients and those who can not tolerate first-line anti-cancer programs to put forward effective treatment options. Sparfloxacin as the basis of medication, according to the specific circumstances of patients with the following drugs 2 to 3 kinds of: INH, RFP, SM, EMB, , Sodium aminosalicylate (PAS), for 25 patients with intensive treatment of the above program for 6 months, each stage are made to observe the detailed records. Results 25 cases were effective in 18 cases, markedly effective in 5 cases, improved in 2 cases, the effective rate was 92%. The group of 25 cases of refractory tuberculosis patients initially achieved a better effect by joint intensive treatment for the clinical treatment of refractory tuberculosis proposed a new program.