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患者女,25岁。2年前无明显诱因停经,体重逐渐由55 kg增加到65 kg,伴腹部紫纹,颈部皮肤发黑,毛发浓密。服用激素治疗后出现月经,但月经量少,颜色发暗,行经3天,伴有脱发,停药后,月经停止。体毛增长,面部变圆,体重增加。体检:血压正常,体型肥胖,满月脸,头发、眉毛浓密,上唇有胡须。颈部、双侧腋下、腘窝可见黑棘皮。皮肤菲薄,可见大量紫纹。实验室检查:皮质醇增多,0 AM:26.2μg/
Female patient, 25 years old. 2 years ago, no obvious incentive for menopause, weight gradually increased from 55 kg to 65 kg, with abdominal bruxism, neck skin black, thick hair. After taking hormone therapy, menstruation, but less menstruation, dark color, after 3 days, accompanied by hair loss, withdrawal, menstruation stopped. Body hair growth, face round, weight gain. Physical examination: normal blood pressure, body fat, full moon face, hair, thick eyebrows, upper beard. Neck, bilateral armpit, popliteal visible black acanthosis. Thin skin, showing a large number of purple lines. Laboratory tests: Cortisol increased, 0 AM: 26.2 μg /