论文部分内容阅读
目的:了解血压控制达标的住院高血压患者降压药使用情况,为临床合理用药提供参考。方法:对3 373例诊断患高血压,出院转归为治愈和好转的住院患者降压药使用情况进行回顾性研究,采用Excel和Access软件统计分析药物品种、使用人数和金额、用药频度(DDDs)、药物利用指数(DUI)及联合用药情况。结果:使用频率与金额居前3位的是钙通道阻滞药(CCB)、血管紧张素Ⅱ受体阻断药(ARB)和血管扩张药;DDDs最高的3个品种为左旋氨氯地平、氨氯地平和缬沙坦。各大类抗高血压药的DUI为0.5～1.1,各品种DUI为0.13～1.84。出现144种用药方案,以单独用药、二联或三联用药为主。结论:住院高血压患者合并症多,联合用药有利于血压控制达标,并降低药物利用指数,我院降压药使用基本合理。
OBJECTIVE: To understand the use of antihypertensive drugs in hospitalized hypertensive patients with blood pressure control standards, and to provide a reference for clinical rational drug use. Methods: A retrospective study was conducted on the use of antihypertensive drugs in 3 373 inpatients diagnosed with hypertension and discharged as a cure and improvement. Excel and Access software were used to statistically analyze drug varieties, number of patients, DDDs), drug utilization index (DUI) and combination therapy. Results: The top three frequency of use and the amount of calcium channel blockers (CCB), angiotensin Ⅱ receptor blocker (ARB) and vasodilators; DDDs the highest three varieties of levamlodipine, Amlodipine and valsartan. The DUI of various types of antihypertensive drugs ranged from 0.5 to 1.1, and the DUI of each variety ranged from 0.13 to 1.84. There are 144 kinds of drug programs to single drug, two or three drug-based. Conclusions: Inpatients with hypertension have more complications, combined with medication is conducive to blood pressure control compliance, and reduce the drug utilization index, the use of antihypertensive drugs in our hospital is reasonable.