本文报道古尼拟青霉(Pacilomyces gunnii)的平喘作用及祛痰作用。通过组胺引起的哮喘动物实验治疗,证明古尼拟青霉5g/kg对哮喘豚鼠具有明显的平喘作用,平喘率达83.3％。本药对脉鼠离体气管平滑肌有轻度松弛作用,并能对抗组胺引起的气管平滑肌的收缩,使收缩高度降低80.2％。同时还有明显的祛痰作用。 This article reports Pacilomyces gunnii’s antiasthmatic effects and expectorant effects. Through experimental treatment of histamine-induced asthma, it was demonstrated that Paecilomyces gonnieri 5g/kg has a significant anti-asthmatic effect on asthmatic guinea pigs, and the asthma rate was 83.3%. The drug has slight relaxation effect on isolated rat tracheal smooth muscle, and can resist histamine-induced contraction of tracheal smooth muscle, reducing the height of contraction by 80.2%. At the same time, there are obvious flaws.