作者报导1例在慢性呼吸衰竭基础上发生的急性呼吸衰竭患者,用纳洛酮后氧饱和度和潮气量均有改善,提示内啡肽在急性呼吸衰竭中起着作用。男性,46岁,有复发性室上性心动过速,后发现右侧横膈麻痹,3个月后自发性恢复。1975年起有白天嗜睡,5年来加重,气急使其只能行走50码,后因呼吸道感染而入院。有喘鸣及右心衰竭,在吸气时腹壁有反常运动。胸部X线片示左侧横膈麻痹。呼吸功能试验结果为:第1秒钟的用力呼气量为0.55升(正常2.6～3.5),用力肺活量1.60升(4.0～5.0),肺总量6.6升(5.9～7.2),残气量4.5升(1.9～2.7)。机械 The authors report that in one patient with acute respiratory failure on the basis of chronic respiratory failure, both naloxone post-nocturnal oxygen saturation and tidal volume improved, suggesting that endorphins play a role in acute respiratory failure. Male, 46 years old with recurrent supraventricular tachycardia, was found to have paralysis of the right diaphragm and spontaneously recover after 3 months. Daytime drowsiness since 1975, five years of aggravating, angst that it can only walk 50 yards, after admission due to respiratory infections. Have wheezing and right heart failure, abdominal wall in breathing abnormal movement. Chest X-ray showed diaphragmatic left paralysis. Respiratory function test results were as follows: forced expiratory volume at 1 second was 0.55 liters (normal 2.6 to 3.5), forced vital capacity at 1.60 liters (4.0 to 5.0), total lung capacity 6.6 liters (5.9 to 7.2), residual capacity 4.5 liters (1.9 ~ 2.7). mechanical