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作者对25例住院病人联用amdinocillin和另外一种β-内酰胺类抗生素治疗。其中肾盂肾炎20例(7例伴菌血症),由放置导管引起的泌尿道感染2例,继发于静脉导管感染的菌血症2例,肺炎1例。受试者均无白细胞减少。曾接受过抗生素24小时以上、青霉素过敏、妊娠或哺乳者均不列入本试验。在分离和确定病原体前开始给药:amdinocillin以10mg/kg混于生理盐水或5％葡萄糖中每隔6小时静脉给药1次。根据病原体的预期敏感性来选择加用氨苄青霉
The authors treated 25 inpatients with amdinocillin and another beta-lactam antibiotic. Among them, 20 cases of pyelonephritis (7 cases with bacteremia), 2 cases of urinary tract infection caused by catheterization, 2 cases of bacteremia secondary to venous catheter infection and 1 case of pneumonia. None of the subjects had leukopenia. Have received antibiotics for more than 24 hours, penicillin allergy, pregnancy or breastfeeding were not included in this test. Administration begins before isolation and identification of pathogens: amdinocillin is administered intravenously once every 6 hours at 10 mg / kg in saline or 5% glucose. According to the expected sensitivity of pathogens to choose plus ampicillin