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急性心肌梗塞(简称AMI)的致命性并发症为室性心律失常和泵衰竭,而其发生率及严重程度均取决于梗塞范围的大。研究发现,在AMI发病早期,梗塞范围是可变的。据此,尽量挽救梗塞边缘区的濒危缺血心肌,为AMI病人保存更多的健全心肌组织,已成为近年来AMI的主要治疗原则。目前,有关这方面的理论和实验研究是心血管病理生理研究工作者和临床心脏病学家最关注的课题之一。此项工作的开展标志着AMI防治研究已发展到一个崭新阶段。现将我们实验室的初步观察报告如下。
Acute myocardial infarction (AMI) fatal complications of ventricular arrhythmias and pump failure, and its incidence and severity are dependent on the scope of the infarct. The study found that, in the early onset of AMI, infarct size is variable. Therefore, it is the main treatment principle of AMI in recent years to try to save the endangered myocardium in the marginal zone of infarction and preserve more healthy myocardial tissue for AMI patients. At present, theoretical and experimental research in this area is one of the most important topics for cardiovascular pathophysiology researchers and clinical cardiologists. This work marks the AMI prevention and control research has developed to a new stage. Now our laboratory observations are as follows.