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糖尿病肾病 (ＤＮ)患者经常伴发凝血、纤溶异常。肝素治疗能有效地降低糖尿病肾病尿蛋白量、改善肾功能〔1〕。但肝素需静脉或 (和 )皮下注射给药 ,长期用药困难。本实验用口服抗凝药苄丙酮香豆素钠 (Ｗａｒｆａｒｉｎ ,华法林 )给ＤＮ患者以观察华法林对糖尿病肾病的疗效。一?
Patients with diabetic nephropathy (DN) often have coagulation and fibrinolysis abnormalities. Heparin treatment can effectively reduce the urinary protein in diabetic nephropathy, improve renal function 〔1〕. However, heparin intravenous or (and) subcutaneous injection, long-term medication difficulties. This experiment with oral anticoagulant coumarin warfarin (Warfarin, warfarin) to DN patients to observe the effect of warfarin on diabetic nephropathy. one?