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目的探讨艾滋病合并肺孢子菌肺炎(PCP)的临床特征。方法回顾性分析6例艾滋病合并PCP的临床资料。结果艾滋病合并PCP常见的临床表现为发热、进行性呼吸困难、咳嗽,较常见的伴随症状为体重下降及水样便。外周血CD4+T淋巴细胞比率下降(2.68±2.69)%,乳酸脱氢酶(LDH)升高(492.50±170.84)U/L,1-3-β-D葡聚糖水平升高(490.53±205.03)pg/ml。高分辨率CT(HRCT)显示非特异性多形性改变。结论艾滋病合并PCP的临床表现具有一定的特征,结合影像学及实验室检查有助于提高该病的早期诊断水平。
Objective To investigate the clinical features of pneumococcal pneumonia (PCP) in AIDS patients. Methods Retrospective analysis of 6 cases of AIDS with PCP clinical data. Results The common clinical manifestations of AIDS complicated with PCP were fever, progressive dyspnea and cough. The more common symptoms were weight loss and watery stools. The ratio of CD4 + T lymphocytes in peripheral blood decreased (2.68 ± 2.69)%, lactate dehydrogenase (LDH) increased (492.50 ± 170.84) U / L, and the level of 1-3- β-D glucan increased 205.03) pg / ml. High-resolution CT (HRCT) showed nonspecific pleomorphic changes. Conclusion The clinical manifestations of AIDS complicated with PCP have certain characteristics. Combined with imaging and laboratory tests, it is helpful to improve the early diagnosis of PCP.