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应用双抗体夹心ＥＬＩＳＡ法测定６７例喉癌，１９例声带息肉患者及３５例正常人血清可溶性白细胞介素Ⅱ受体（ｓＩＬ－２Ｒ水平、结果表明：喉癌患者的血清ｓＩＬ－２Ｒ水平明显高于声带息肉患者和正常人（Ｐ＜０．０１）。且喉癌病人的血清ｓＩＬ－２Ｒ水平与喉癌的病理分化程度、临床分型、分期及手术前后均具有明显的相关趋势。提示血清ｓＩＬ－２Ｒ水平的检测可作为喉癌患者临床监测指标之一。
Serum soluble interleukin-2 receptor (sIL-2R) levels were measured in 67 patients with laryngeal cancer, 19 patients with vocal cord polyps and 35 normal controls by double antibody sandwich ELISA. The results showed that serum sIL-2R levels were significantly higher in laryngeal cancer patients (P <0.01). The serum sIL-2R level in laryngeal cancer patients was significantly correlated with the degree of pathological differentiation, clinical type, stage and preoperative and postoperative of laryngeal cancer.It was suggested that serum The detection of sIL-2R level can be used as one of the clinical monitoring indicators of laryngeal cancer patients.