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目的:评价空腹血糖(Fasting plasma glucose,FPG)与糖化血红蛋白(Glycosylated hemog lobin al c,HbA1c)在糖尿病(Diabetes mellitus,D M)诊断和监控中的临床应用价值。方法 :将130例糖尿病患者作为糖尿病组,150例健康体检者作为对照组,通过葡萄糖氧化酶法测定FPG,高效液相层析法测定HbA1c,并对其结果进行比较。结果:糖尿病组FPG和HbA1c水平均明显高于对照组,差异有统计学意义(P<0.05)。结论:FPG与HbA1c两者关系密切,分别为糖尿病患者提供即时和长期的血糖信息,联合检测患者FPG和HbA1c对糖尿病的早期发现、诊断和监控有重要意义。
Objective: To evaluate the clinical value of fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) in the diagnosis and surveillance of diabetes mellitus (DM). Methods: 130 diabetic patients were selected as the diabetic group and 150 healthy controls as control group. FPG was determined by glucose oxidase method and HbA1c was determined by HPLC. The results were compared. Results: The levels of FPG and HbA1c in diabetic group were significantly higher than those in control group (P <0.05). Conclusion: Both FPG and HbA1c are closely related to provide immediate and long-term blood glucose information for diabetic patients. Combined detection of FPG and HbA1c in patients with early detection of diabetes is of great significance.