Adult hippocampal neurogenesis (AHN) facilitates hippocampal circuits plasticity and regulates hippocampus- dependent cognition and emotion. However, AHN malfunc-tion has been widely reported in both human and animal models of Alzheimer\'s disease (AD),
Alzheimer\'s disease (AD) is a neurodegenerative disorder. The pathology of AD is characterized by extracellular amyloid beta (Aβ) plaques, neurofibrillary tangles com-posed of hyperphosphorylated tau, neuronal death, synapse loss, and brain atrophy. Ma
Alzheimer\'s disease and Parkinson\'s disease are two of the most prevalent and disa-bling neurodegenerative diseases globally. Both are proteinopathic conditions and while occasionally inherited, are largely sporadic in nature. Although the advances
年,甲骨文里的写法是“上禾下人”.《说文解字》里说,“年,谷熟也”,引申为一年的收成、年纪、年节、年代等.年还是时间单位,地球环绕太阳公转一次,需365天又1/4太阳日,是为一年.rn正所谓民以食为天.我们所有的节日,都有一个不约而同的庆祝方式:“吃啥?!”尤其是等了365天才等到的,既是结束又是开始的年,更得隆重行事.
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed single- stranded transcript. They are a novel class of genomic regulators that are linked to many important development and disease processes and are being pursued as clinical and thera
The mdx mouse is a model of Duchenne muscular dystrophy (DMD), a fatal progres-sive muscle wasting disease caused by dystrophin deficiency, and is used most widely in preclinical studies. Mice with dystrophin deficiency, however, show milder muscle streng
Background : Anoxic brain injuries represent the main determinant of poor outcome after cardiac arrest (CA). Large animal models have been described to investigate new treatments during CA and post- resuscitation phase, but a detailed model that includes
俗话说,“舒服不过倒着,好吃不过饺子”.确实,饺子好吃,很多人都喜欢吃饺子.如果想吃的话,我们可以天天吃饺子.rn张仲景与饺子的故事rn饺子最开始叫做“娇耳”,还有“扁食”“饺饵”“粉角”等叫法.饺子来源于我国古代的“角子”,是从馄饨逐步演变来的.别小看小小的饺子,它已经有1800多年的历史了.
Background : Largely due to incidental detection, asymptomatic pancreatic cystic le-sions (PCLs) have become prevalent in recent years. Among them, intraductal papillary mucinous neoplasm (IPMN) infrequently advances to pancreatic ductal adenocarci-noma (
Background : Porcine pancreatic elastase (PPE) is successfully used to induce abdomi-nal aortic aneurysm (AAA) in mice. However, differences between mouse strains in susceptibility to PPE induction have been reported. Kunming mouse is one of the most freq