论文部分内容阅读
目的：测定Ⅱ型糖尿病并高脂血症患者血浆纤维蛋白原水平，并观察多烯康胶丸（ＤＸｋ）对其影响。方法：应用比浊法测定２１例Ⅱ型糖尿病并高脂血症患者和２２例健康查体者（ＮＣ）血浆纤维蛋白原（Ｆｇ）水平。１１例患者继续用Ｄｘｋ（２ｃａｐｓ，ｔｉｄ，ｐｏ）治疗，治疗４周后观察Ｄｘｋ对Ｆｇ和血胆固醇（ＴＣ）及血甘油三酯（ＴＧ）的影响。结果：２１例病人血浆Ｆｇ水平均显著高于ＮＣ组（Ｐ＜０．０１）。１１例病人经过Ｄｘｋ４周治疗后，血浆Ｆｇ水平由２．９４±０．４７ｇ／Ｌ下降至２．６２±０．４８ｇ／Ｌ（Ｐ＜０．０５），ＴＣ由６．５７±１．１５ｍｍｏｌ／Ｌ降至５．９９±０．７１ｍｍｏｌ／Ｌ（Ｐ＜０．０５），ＴＧ由１．８５±０．４２ｍｍｏｌ／Ｌ降至１．７５±０．３８ｍｍｏｌ／Ｌ（Ｐ＞０．０５）、结论：糖尿病并高脂血症患者体内Ｆｇ水平明显升高，Ｄｘｋ能降低Ｆｇ水平。
Objective: To determine the level of plasma fibrinogen in patients with type Ⅱ diabetes mellitus and hyperlipidemia and observe the effect of DXk. Methods: The levels of fibrinogen (Fg) in 21 patients with type Ⅱ diabetes mellitus and 20 patients with hyperlipidemia and 22 healthy controls were measured by turbidimetry. Eleven patients continued treatment with Dxk (2caps, tid, po) for 4 weeks and observed the effect of Dxk on Fg, TC and triglyceride (TG). Results: The plasma levels of Fg in 21 patients were significantly higher than those in NC group (P <0.01). Eleven patients after Dxk 4 weeks treatment, plasma Fg levels decreased from 2.94 ± 0.47g / L to 2.62 ± 0.48g / L (P <0.05), TC from 6.57 ± 1.15mmol / L to 5.99 ± 0.71mmol / L (P <0.05), TG decreased from 1.85 ± 0.42mmol / L to 1.75 ± 0.38mmol / L (P> 0.05) Conclusion: The level of Fg in diabetic patients with hyperlipidemia was significantly increased, and Dxk could reduce the level of Fg.