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目的了解广州市中学生结核菌素反应状况,为开展结核病预防用药提供参考数据。方法由结核病防治专业人员对970名中学生进行结核菌素试验(PPD试验)调查,并对其反应结果进行分析。结果 PPD试验人数970人,阳性反应683人,阳性率为70.4%。其中初中学生PPD试验101人,阳性反应78人,阳性率为77.2%,;高中学生PPD试验869人,阳性反应605人,阳性率为70.0%,初、高中学生PPD反应一般阳性率没有差异(P>0.05)。强阳性反应141人,强阳性反应率20.6%,其中初中学生强阳性反应29人,强阳性反应率28.7%;高中学生强阳性反应112人,强阳性反应率13.0%,初中学生强阳性反应率高于高中学生,两者差异有显著性(P<0.05)。此外,有卡痕者PPD试验阳性者和无卡痕者PPD试验阳性者的反应率差异无显著性(P>0.05)。结论建议定期采用结核菌素对中学生进行结核病监测工作,可把结核菌素试验反应硬结平均径≥15 mm的强阳性反应者列为预防性治疗对象,以减少中学生结核病的发生。
Objective To understand the status of tuberculin reaction in secondary school students in Guangzhou and to provide reference data for the prevention of tuberculosis. Methods A total of 970 secondary school students were tested for tuberculin test (PPD test) by TB prevention and control professionals, and their response results were analyzed. Results The number of PPD test 970 people, 683 were positive, the positive rate was 70.4%. Among them, 101 were PPD test of junior high school students, 78 were positive, the positive rate was 77.2%; 869 high school students PPD test, 605 positive, the positive rate was 70.0% P> 0.05). Strong positive reaction of 141 people, strong positive response rate of 20.6%, of which junior high school students strong positive reaction of 29 people, strong positive response rate of 28.7%; high school students strong positive reaction of 112 people, strong positive response rate of 13.0%, junior high school students strong positive response rate Higher than high school students, the difference was significant (P <0.05). In addition, there was no significant difference (P> 0.05) in the response rate between those with positive PPD test and those without PPD test. Conclusions It is suggested that tuberculin should be used regularly to monitor tuberculosis in middle school students, and strong positive responders with tuberculous test induration average diameter ≥15 mm may be listed as prophylactic treatment to reduce the incidence of TB among middle school students.