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肿瘤学中以转移性乳腺癌化疗的有效率为最高,但完全缓解率和生存的时间并没有明显增加。为此,作者探索乳腺癌术后化疗及转移病变更有效的治疗方法以提高其疗效.在单个化疗药物中,环磷酰胺(CTX)和氟脲嘧啶(5-Fu)是抗乳腺癌最有效的药物。1978年以来,对30例以前没有接受过化疗,或转移部位没接受过放疗的转移性乳腺癌病人,应用高剂量CTX 和5-Fu 联合治疗。女性29例,其中绝经后15例,男性一例。平均年龄54岁(35～78岁)。22例局部切除和/或放疗后转移,平均缓解期为34个月(12～49个月),其余8例同时有原发肿瘤和转移
The effective rate of chemotherapy for metastatic breast cancer was highest in oncology, but the complete remission rate and survival time did not increase significantly. To this end, the authors explore effective treatments for postoperative chemotherapy and metastasis of breast cancer to improve its efficacy. Among individual chemotherapy drugs, cyclophosphamide (CTX) and 5-fluorouracil (5-Fu) are the most effective against breast cancer. Drug. Since 1978, a combination of high-dose CTX and 5-Fu has been used in 30 patients with metastatic breast cancer who have not previously received chemotherapy or who have not received radiotherapy at the site of metastasis. There were 29 females, of whom 15 were postmenopausal and 1 male. The average age is 54 years old (35-78 years old). After 22 cases of local resection and/or metastasis after radiotherapy, the average remission period was 34 months (12 to 49 months). The remaining 8 cases had both primary tumor and metastasis.