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目的分析南平市2010-2015年流行性感冒(流感)流行特征及流感病毒毒株型别,为流感防控提供科学依据。方法采集南平市两家哨点医院流感样症状的病例咽拭子标本,用细胞培养法进行病毒分离,并从中国流感监测信息系统中收集南平市监测点流感样病例(influenza-like illness,ILI)数据。结果2010-2015年采集流感样病例咽拭子标本8 567份,用MDCK细胞培养分离毒株709株,阳性率8.28%,主要流感病毒型别为新甲型H1N1型,占3.05%;A型H3,占1.25%;B型BV占2.37%,BY占1.60%;其中2010年病毒型别以新甲型H1N1型和BY型(Yamagate)为流行优势株,2011年以BV型(Victoria)和新甲型H1N1型为流行优势株,2012年主要以BV型(Victoria)为流行优势株,2013年以新甲型H1N1型和季节性H3(H3N2)为流行优势株,2014年以新甲型H1N1型为流行优势株,2015年以BY型(Yamagate)为流行优势株。不同监测月份流感病毒分离率最高为1月份(22.48%),最低为9月份(0.44%)。结论 2010-2015年南平市流感病毒新甲型H1N1、季节性H3、B型同时在人群中交替流行,以新甲型H1N1型和B型为主,每年主要流行优势株交替出现。发病高峰在冬春季。
Objective To analyze the epidemiological characteristics of influenza (influenza) and strain types of influenza viruses in Nanping from 2010 to 2015, and provide a scientific basis for prevention and control of influenza. Methods Throat swab specimens were collected from two sentinel hospitals in Nanping City for virus isolation. Cell culture was used for virus isolation. Influenza-like illness (ILI) was collected from the China Influenza Surveillance Information System )data. Results A total of 8 567 throat swab samples were collected from 2010 to 2015. 709 strains were isolated from MDCK cells and the positive rate was 8.28%. The main influenza virus type was new type A H1N1 (3.05%). Type A H3 accounted for 1.25%; B type BV accounted for 2.37%, BY accounted for 1.60%; of which the virus type in 2010 to the new influenza A H1N1 and BY type (Yamagate) prevalence strains in 2011 to BV type (Victoria) and The new H1N1 strain was the predominant strain. In 2012, the predominant strain belonged to the predominant strain of BV (Victoria). In 2013, the new strain of influenza A (H1N1) and seasonal H3 (H3N2) H1N1 is a predominant strain, and in 2015, BY-type (Yamagate) was the predominant strain. The highest isolation rate of influenza virus in different months was January (22.48%) and the lowest was September (0.44%). Conclusions From 2010 to 2015, the influenza A (H1N1) and seasonal H3 and B viruses of the Nanping City were simultaneously prevalent in the population. Influenza A (H1N1) and type B (B) were predominant in the population. Major epidemic dominant strains appeared alternately each year. Peak incidence in winter and spring.