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目的 :探讨和验证前列痛栓治疗前列腺痛的药效。方法 :采用小鼠肛门给药 ,以空白、消炎痛栓为对照组 ,测定前列痛栓对小鼠扭体次数、网状内皮系统吞噬指数、耳廓肿胀、肉芽增生及大鼠小肠肌电的影响。结果 :前列痛栓能明显减少小鼠扭体次数 ,优于消炎痛栓 ;对网状内皮系统吞噬功能、二甲苯所致小鼠耳廓肿胀和滤纸片埋入形成的肉芽增生及大鼠小肠肌电的影响 ,与消炎痛栓相近。结论 :前列痛栓治疗前列腺痛有显著的镇痛作用
Objective: To explore and verify the efficacy of Qianlietong suppository in the treatment of prostate pain. METHODS: Anal administration was performed in mice, and blank and indomethacin suppositories were used as control groups to determine the number of writhings of mice treated with Qianlietong suppository, phagocytic index of reticuloendothelial system, auricular swelling, granulation hyperplasia, and myoelectricity of rat small intestine. influences. RESULTS: Qianlietong suppository can significantly reduce the number of writhing in mice, better than that of indomethacin suppository, phagocytosis of reticuloendothelial system, swelling of mouse ear caused by xylene, and granulation proliferation formed by filter paper and rat small intestine The influence of myoelectricity is similar to that of indomethacin. Conclusion: Qianlietong suppository has significant analgesic effect on prostate pain