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由内镜和病理确诊的胃和十二指肠球溃疡患者共２４０名，给予甘草锌治疗６周。治疗前后以ＡＨ一６３０－０１型原子吸收分光光度计和ＲＦ一５４０型荧光分光光度计，测定其病变组织中Ｆｅ、Ｚｎ、Ｃｕ、Ｍｎ、Ｓｅ的含量。结果：①胃和十二指肠球溃疡者的Ｆｅ、Ｚｎ、Ｓｅ水平，治疗后较治疗前有明显提高，有显著性差异，Ｐ＜０．０５或Ｐ＜０．０１。②胃和十二指肠球溃疡者的Ｚｎ／Ｆｅ、Ｚｎ／Ｃｕ、Ｚｎ／Ｍｎ、Ｌｎ／Ｓｅ比位治疗后较治疗前有显著性或高度显著性差异，Ｐ＜０，０５或Ｐ＜０．０１。③全部患者锌治疗６周后，临床主要症状消失，疗效满意。
A total of 240 patients with gastric and duodenal ulcer diagnosed by endoscopy and pathology were given glycyrrhizin for 6 weeks. Before and after treatment, the content of Fe, Zn, Cu, Mn and Se in the diseased tissues were measured by AH-630-01 atomic absorption spectrophotometer and RF-540 fluorescence spectrophotometer. Results: ① The levels of Fe, Zn and Se in patients with gastric ulcer and duodenal ulcer were significantly higher than those before treatment, P <0.05 or P <0.01. ② The ratio of Zn / Fe, Zn / Cu, Zn / Mn and Ln / Se in patients with gastric ulcer and duodenal ulcer had significant or highly significant difference compared with that before treatment, P <0,05 or P < 0.01. ③ All patients with zinc treatment for 6 weeks, the main clinical symptoms disappeared, the effect was satisfactory.