原发性十二指肠腺癌甚少见,但由于窥镜的广泛应用,国内外报导的病例数显著增加。有的文献报告,十二指肠腺癌的发病率在胃肠道恶性肿瘤中占0.3％小肠恶性肿瘤与25—45％。由于本病早期临床无特征性表现,故诊断困难,发现时常属晚期,予后不良,5年生存率甚低,现将我院1976—1983年开展内窥镜捡查和病理组织学证实十二指肠腺癌6例报告如下: 临床资料本组病例最低年令44岁,最高年令67岁,全部是男性。 Primary duodenal adenocarcinoma is rarely seen, but due to the extensive use of speculum, the number of cases reported at home and abroad has increased significantly. Some literature reports that the incidence of duodenal adenocarcinoma accounts for 0.3% of small intestinal malignancies and 25-45% of gastrointestinal cancers. Due to the clinically uncharacteristic performance of the disease in the early stage, it was difficult to diagnose. It was often found to be late, with poor prognosis, and a very low 5-year survival rate. The endoscopic examination and histopathology confirmed in our hospital from 1976 to 1983. Two cases of adenocarcinoma of the duodenum were reported as follows: Clinical data The minimum age of the patients in this group was 44 years old, and the maximum age was 67 years old. All of them were male.