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以 RIA 检测了成人牙周炎(AP)10人20个牙治疗前后和牙周健埭者(H)10人21个牙龈沟液(GCF)中β_2-微球蛋白(β_-MG)的含量并记录临床指数 PLI、GI、PD、AL。结果显示:AP 组 GCF 中β_2-MG 的含量显著小于 H 组(P<0.01);在 H 组、AP 组混合情况下和 AP 组内,β_2-MG 含量只与 PD、AL 呈显著负相关(P<0.05);牙周治疗后,随着牙周破坏程度的减轻(P<0.01),β_2-MG 的含量相应升高(P<0.05),说明 GCF 中β_2-MG 与牙周破坏程度有关,并可能参与了 AP 的局部免疫反应。
The contents of β_2-microglobulin (β_-MG) in 21 gingival crevicular fluid (GCF) of 10 individuals with adult periodontitis (AP) were detected by RIA and recorded Clinical index PLI, GI, PD, AL. The results showed that the content of β_2-MG in GCF of AP group was significantly lower than that of H group (P <0.01). In the combination of H group and AP group, the content of β_2-MG in APF group was only negatively correlated with PD and AL (P <0.05). After periodontal treatment, the content of β_2-MG increased correspondingly with the reduction of periodontal destruction (P <0.01), indicating that β_2-MG in GCF was related to the degree of periodontal destruction , And may be involved in the local immune response of AP.