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核酸酶P_1(EC 3.1.30)是一个具有水解核酸(RNA和DNA)功能的含锌金属酶,其水解产物是组成RNA或DNA的结构单元——四种5’-核苷单磷酸或四种5’-脱氧核苷单磷酸. 金属离子在一定的条件下,可能与酶、核酸或核苷酸形成配合物,从而影响酶催化的水解核酸反应.
The nuclease P_1 (EC 3.1.30) is a zinc-containing metalloenzyme having the function of hydrolyzing nucleic acids (RNA and DNA) whose hydrolyzate is a constituent unit constituting RNA or DNA - four kinds of 5’-nucleoside monophosphate or tetrakis 5’-deoxynucleoside monophosphate metal ions under certain conditions, enzymes, nucleic acids or nucleotides may form complexes, thus affecting the enzyme catalyzed hydrolysis of nucleic acid reaction.