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由胸腺产生的抗胸腺素α-1(一种激素抗体)可为发展AIDS疫苗提供线索。美国国立癌症研究所和乔治华盛顿大学的科学家发现胸腺素α-1及AIDS病毒核心中的gag蛋白有一个44～50％类似的18个氨基酸的序例。抗胸腺素α-1(Τα-1)抗体在体外H9细胞中能中和AIDS病毒并抑制其复制。这项研究工作提示,与gag蛋白相似的肽可能用作AIDS疫苗。科学家进一步使用病毒技术产生gag蛋白,然后将其注入动物体内,观察是否产生抗gag蛋白抗体。如果产生抗体并有效地对抗AIDS病毒,此蛋白将作
Anti-thymosin alpha-1 (a hormone antibody) produced by the thymus may provide clues for the development of AIDS vaccines. Scientists at the National Cancer Institute and the George Washington University found that gag proteins in the thymosin alpha-1 and AIDS virus nuclei have a 44-50% similar 18-amino acid sequence. Anti-thymosin alpha-1 (Tα-1) antibody neutralizes AIDS virus and inhibits its replication in vitro in H9 cells. This work suggests that peptides similar to gag may be used as AIDS vaccines. Scientists further use the virus technology to produce gag protein, which is then injected into animals to see if anti-gag antibodies are produced. If antibodies are produced and are effective against the AIDS virus, this protein will be made