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目的:评价曲美他嗪对冠脉多支病变血运重建不完全患者的疗效。方法:选择冠脉多支病变血运重建不完全患者82例,随机分为治疗组及对照组,两组均于介入治疗后行常规治疗,同时治疗组还口服曲美他嗪,观察两组心功能、心绞痛的改善及心血管事件的发生。结果:治疗组与对照组比较总有效率为92.9%∶80.0%(P<0.05),较之对照组,治疗组的心功能有明显改善,复发心绞痛明显减少(P均<0.05),治疗组的心血管事件较对照组减少,但无统计学意义。结论:在常规治疗的基础上加用曲美他嗪对冠脉多支病变血运重建不完全的患者有一定疗效。
Objective: To evaluate the efficacy of trimetazidine in patients with incomplete coronary revascularization. Methods: Eighty-two patients with incomplete coronary revascularization were randomly divided into treatment group and control group. Both groups were treated routinely after interventional therapy. Trimetazidine was also given orally in the treatment group. Two groups Improvement of heart function, angina pectoris and occurrence of cardiovascular events. Results: Compared with the control group, the total effective rate of the treatment group and the control group was 92.9% and 80.0% respectively (P <0.05). Compared with the control group, the cardiac function of the treatment group was significantly improved and the recurrent angina pectoris was significantly reduced (P <0.05) Cardiovascular events than the control group decreased, but not statistically significant. Conclusion: The addition of trimetazidine on the basis of routine treatment has some curative effect on patients with incomplete coronary revascularization.