环核苷酸类主要指的是cAMP及cGMP。自1957年Sutherland发现cAMP以后,进行了大量研究工作,证明cAMP是体内非常活跃的物质。此后,1963年Price等又发现了cGMP,并有很多研究工作证明cAMP和cGMP在生命活动中起着很重要的作用,它涉及到生理、生化、药理、病理、免疫等许多方面,并渗透到临床各科,在中西医结合的理论研究方面也日益显示其重要意义。由于文献丰富,二者作用广泛,限于篇幅,不能一一述及,谨择其要者,作一介绍。 Cyclic nucleotides mainly refer to cAMP and cGMP. Since the discovery of cAMP in 1957, Sutherland has done a lot of research to prove that cAMP is a very active substance in the body. Since then, Price found cGMP again in 1963 and many studies have proved that cAMP and cGMP play an important role in life activities. They involve many aspects such as physiology, biochemistry, pharmacology, pathology and immunity, and permeate into Clinical subjects, in the theory of traditional Chinese and Western medicine is also increasingly revealing its significance. Due to the rich literature, both of them have a wide range of functions and are limited in length. They can not be mentioned one by one.