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甘草酸二铵是治疗肝炎的新药。本文采用甘草酸二铵对28例慢性活动性肝炎患者进行了治疗，疗程1个月，总有效率为93％与对照组（71％）相比差别有显著性（P＜0.05），和强力宁治疗组（95％）相比差别无显著性（P＞0.05）。在治疗同时，对单核吞噬细胞的吞噬功能、各类免疫球蛋白含量及T淋巴细胞亚群的变化进行了测定．结果甘草酸二铵组IgM水平治疗后比治疗前显著降低（P＜0.05），单核细胞吞噬率明显增高（P＜0.05），CD4细胞明显增高、CD8细胞明显降低，CD4／CD8的比值增高（P＜0.05）。提示甘草酸二铵对慢性活动性肝炎有明显的治疗作用，且可增强机体细胞免疫功能。
Diammonium glycyrrhizinate is a new drug for the treatment of hepatitis. In this paper, 28 patients with chronic active hepatitis were treated with diammonium glycyrrhizinate. The course of treatment was 1 month, the total effective rate was 93%, which was significantly different from that of the control group (71%) (P <0.05) Ning treatment group (95%) was no significant difference (P> 0.05). At the same time of treatment, the phagocytic function of mononuclear phagocytes, the content of various immunoglobulins and the changes of T lymphocyte subsets were determined. Results The levels of IgM in glycyrrhizic acid diammonium group were significantly lower than those before treatment (P <0.05), the monocyte phagocytosis rate was significantly increased (P <0.05), the number of CD4 cells was significantly increased, the number of CD8 cells was significantly decreased and the ratio of CD4 / CD8 was increased (P <0.05). Tip diammonium glycyrrhizinate chronic active hepatitis have obvious therapeutic effect, and can enhance the body’s cellular immune function.