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既往的研究认为恶性疟裂殖子侵入红细胞系受红细胞表面受体所调节,其中的糖蛋白A是红细胞表面受体。另外还有两个红细胞表面组分也可能是裂殖子侵入红细胞的抑制剂,其一是带3(红细胞膜的运输糖蛋白),其二是具有抗原决定因子的大分子,带3的量在红细胞膜上很多,因此作者用体外法观察了此二个膜组分的抑制效果,并提取和观察了另一个主要含有唾液糖蛋白而去除带3的脱脂糖蛋白的作用。
Previous studies have suggested that P. falciparum invades the erythrocyte lineage under the regulation of erythrocyte surface receptors, of which glycoprotein A is the erythrocyte surface receptor. There are also two other erythrocyte surface components that may also be inhibitors of merozoite intrusion into erythrocytes, one of which is a transporter glycoprotein with band 3 (erythrocyte membrane) and the second is a macromolecule with an antigenic determinant, the amount of band 3 On the erythrocyte membrane, the authors observed the inhibitory effect of these two membrane components by an in vitro method and extracted and observed the effect of removing the deglycosylated glycoprotein of band 3, which mainly contains salivary glycoprotein.