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目的 探讨围产期淋球菌（Ｎｇ） 解脲脲原体（Ｕｕ） 和沙眼衣原体（Ｃｔ） 感染［ 以下简称ＮＵＣ 感染］ 可能存在的母婴传播途径。方法 配对采集孕妇宫颈脱落细胞与羊水和孕妇宫颈脱落细胞与新生儿咽拭子标本，应用灵敏、特异、准确的套式聚合酶链式反应（ｎＰＣＲ） 技术检测上述标本中的ＮＵＣ 特异性ＤＮＡ，并作相关性分析。结果分析 １－ 羊水ＮＵＣ阳性检出率与孕妇宫颈部ＮＵＣ感染与否不相关（Ｐ＞ ０．０５） ，表明羊水中ＮＵＣ来源不仅仅是宫颈部病原体的上行传播，可能存在血行传播，２－ 阴道分娩的新生儿咽拭子ＮＵＣ 阳性检出率达３８－５ ％ ，明显高于剖腹产新生儿的２０－５ ％ （Ｐ＜０－０５），表明经产道感染现象的存在，且较为严重。
Objective To investigate possible maternal-to-infant transmission of Uu and Ct infections in Neisseria gonorrhoeae (Ng) [hereafter referred to as NUC infection]. Methods Pair of cervical exfoliated cells from pregnant women, amniotic fluid and pregnant women with cervical exfoliated cells and neonatal throat swabs were collected. The sensitive, specific and accurate nested PCR (nPCR) technique was used to detect the NUC specific DNA, And make correlation analysis. Results The positive rate of NUC in 1-amniotic fluid was not correlated with the cervical NUC in pregnant women (P> 0.05), indicating that the source of NUC in amniotic fluid is not only the upwards transmission of cervical pathogens, Neonatal vaginal delivery of throat swab NUC positive detection rate of 38-5%, significantly higher than caesarean section of newborns 20-5% (P <0-05), indicating that the phenomenon of the birth canal infection, and more serious.