论文部分内容阅读
目的测定糖化血清蛋白(Glucosylated serum proteins,GSP)含量,探讨在Ⅱ型糖尿病的诊断和治疗中的临床价值。方法采用酶法测定Ⅱ型糖尿病患者与正常对照组糖化血清蛋白和葡萄糖含量,并进行相对应比较。结果101例Ⅱ型糖尿病患者的GSP含量高于正常对照组,二者差异有统计学意义(P<0.01);其中61例II型糖尿病患者治疗前与治疗后(第1周和第2周)相比较,血糖结果有显著性差异(P<0.01);而GSP含量无显著性差异(P>0.05)。结论测定GSP含量,不仅可以作为糖尿病诊断的重要指标,也是评价糖尿病患者近期病情控制和疗效监控的一项可靠指标。
Objective To determine the content of Glucosylated serum proteins (GSP) and to explore its clinical value in the diagnosis and treatment of type Ⅱ diabetes mellitus. Methods Enzymatic determination of glycated serum albumin and glucose in patients with type 2 diabetes mellitus and normal control group, and the corresponding comparison. Results The GSP content in 101 patients with type Ⅱ diabetes mellitus was significantly higher than that in the normal control group (P <0.01). Among the 61 patients with type 2 diabetes mellitus before and after treatment (week 1 and week 2) There was significant difference in blood glucose (P <0.01), but there was no significant difference in GSP (P> 0.05). Conclusion The determination of GSP content not only can be used as an important index in the diagnosis of diabetes, but also a reliable indicator to evaluate the recent condition control and curative effect monitoring of diabetic patients.