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最近,美国食品和药物管理局已批准吡喹酮(Biltricide)用以治疗各型血吸虫病。该药对其他吸虫和绦虫感染也有效,是抗蠕虫化学治疗的一个较大进展。吡喹酮具有高效、广谱、低毒的优点,可顿服或分服。药理作用吡喹酮(2-环己酰基-[1,2,3,6,7,116]-6氢-4氢-吡嗪并[2,1-α]-异喹啉-4-酮)是有突出的广谱抗蠕虫作用。口服后吸收迅速,代谢物经过明显的首次生化转变,在尿中排出。健康成人口服50mg/kg 1～2小时后血
Recently, the U.S. Food and Drug Administration has approved the use of Biltricide to treat various types of schistosomiasis. The drug is also effective against other fluke and tapeworm infections and represents a major advance in anthelmintic chemotherapy. Praziquantel has the advantages of high efficiency, broad spectrum, low toxicity, Dayton clothing or sub-service. Pharmacological Effects Praziquantel (2-cyclohexanoyl- [1,2,3,6,7,116] -6-hydro-4H-pyrazino [2,1-a] -isoquinolin- Prominent broad-spectrum anthelmintic effect. Absorbed rapidly after oral administration, metabolites after significant first-time biochemical changes, excreted in the urine. Healthy adults oral 50mg / kg 1 to 2 hours after the blood