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120例自愿要求人流的患者随机分成治疗组与对照组各60例。治疗组术前2d口服米非司酮并于术前1h阴道置米索前列醇,对照组人工流产前不服用任何药物。对比两组在手术成功率、宫口松弛程度、术中出血量、手术时间、术后不良反应等方面的差异。结果治疗组完全流产率、宫口松弛总有效率均高于对照组,两组差异具有统计学意义。治疗组术中出血量、手术时间及不良反应发生率均少于对照组,两组各项差异均具有统计学意义。
One hundred and twenty patients who voluntarily requested abortion were randomly divided into treatment group (60 cases) and control group (60 cases). The patients in the treatment group were given mifepristone 2 days before operation and vaginal misoprostol 1 h before surgery. The control group did not take any drugs before the abortion. The differences between the two groups in the success rate of surgery, the degree of cervix relaxation, intraoperative blood loss, operation time, and postoperative adverse reactions were compared. Results The complete abortion rate and the total effective rate of cervix relaxation in the treatment group were higher than those in the control group, with significant difference between the two groups. The blood loss, operation time and incidence of adverse reactions in the treatment group were less than those in the control group, and the differences between the two groups were statistically significant.