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目的 :研究左旋咪唑致脱髓鞘脑病的临床及 CT、MRI的诊断价值。方法 :分析 2 6例左旋咪唑致脱髓鞘脑病的临床及 1 8例 CT、2 0例 MRI资料。结果 :本病的主要临床表现为急性或亚急性起病的弥漫性脑损害。 1例脑活检显示脱髓鞘病灶。皮质激素治疗效果好。1 3例 CT及 2 0例 MRI显示脑白质区有多发病灶 ,CT为低密度影 ,MRI为长 T1 长 T2 信号 ,仅 1例有占位效应。MRI的影像学诊断率明显高于 CT。结论 :本病的诊断依靠其临床特点和影像学检查 ,MRI的诊断价值明显优于 CT。
Objective: To study the clinical value of levamisole-induced demyelinating encephalopathy and the diagnostic value of CT and MRI. Methods: The clinical data of 26 levamisole-induced demyelinating encephalopathy cases and 18 cases of CT and 20 MRI data were analyzed. Results: The main clinical manifestation of this disease is diffuse brain damage of acute or subacute onset. One case of brain biopsy showed demyelinating lesions. Good corticosteroid treatment. Thirteen cases of CT and 20 cases of MRI showed multiple lesions in white matter, CT was low density, MRI is long T1 long T2 signal, only one case has a mass effect. MRI imaging diagnosis rate was significantly higher than CT. Conclusion: The diagnosis of this disease depends on its clinical features and imaging examination. The diagnostic value of MRI is better than that of CT.