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目的:对比分析餐前短效胰岛素加甘精胰岛素和胰岛素泵短期强化治疗对2型糖尿病的治疗效果。方法:按照随机原则将80例2型糖尿病患者分成对照组和实验组各40例,对照组患者给予胰岛素泵短期强化治疗,实验组患者则给予餐前短效胰岛素加甘精胰岛素治疗;治疗12周后对两组患者的临床疗效进行对比分析。结果:治疗后两组患者的FBG、2h PBG水平均显著降低,但是组间比较差异无统计学意义(P>0.05);另外实验组患者的胰岛素用量、治疗成本显著低于对照组患者(P<0.05),低血糖发生次数显著多于对照组患者(P<0.05)。结论:临床中在对2型糖尿病患者进行治疗时,餐前短效胰岛素加甘精胰岛素和胰岛素泵短期强化治疗均能取得比较理想的效果,餐前短效胰岛素加甘精胰岛素治疗能让胰岛素用量和患者的治疗成本降低,但是却会增加低血糖发生几率。
Objective: To compare and analyze the therapeutic effect of short-acting pre-prandial insulin plus insulin glargine and short-term intensive insulin pump on type 2 diabetes mellitus. Methods: Eighty patients with type 2 diabetes were divided into control group and experimental group according to the random principle. Forty patients in the control group were treated with short-term intensive insulin pump. Patients in the experimental group were treated with fasting insulin and insulin glargine. Week after the two groups of patients for clinical efficacy comparative analysis. Results: The levels of FBG and 2 PBG in both groups were significantly decreased after treatment, but there was no significant difference between the two groups (P> 0.05). In addition, the insulin dosage and the treatment cost of the experimental group were significantly lower than those of the control group (P <0.05), the incidence of hypoglycemia was significantly more than that of the control group (P <0.05). Conclusion: In the treatment of type 2 diabetes patients in the clinical trials, short-acting insulin plus insulin glargine and insulin pump short-term intensive treatment can achieve the desired effect, short-acting insulin plus insulin glargine insulin can make insulin Dosage and treatment costs for patients decrease, but will increase the incidence of hypoglycemia.