论文部分内容阅读
本文分析57例恶性小凶细胞肿瘤(MSRCT)免疫组化表型及病理形态。结果表明:兔抗鸡结蛋白及(或)兔抗人肌红蛋白可作为横纹肌肉瘤的标志;神经母细胞瘤、嗅神经母细胞瘤及原始外周神经外胚层瘤的免疫组化特征为NSE阳性,而Vim阴性;抗NSE抗血清特异性差,其他MSRCT亦可与之反应。尤文肉瘤Vim阳性,有些病例NSE阳性。未分化滑膜肉瘤Vim阳性;部分病例Ker及(或)EMA阳性,可有假阴性。LCA是恶性淋巴瘤特异性标记。α_1-ACT对MSRCT鉴别诊断无价值。
This article analyzed the immunohistochemical phenotype and pathological features of 57 malignant virulent cell tumors (MSRCT). The results showed that rabbit anti-chicken protein and/or rabbit anti-myoglobin could be used as a marker of rhabdomyosarcoma; the immunohistochemical characteristics of neuroblastoma, olfactory neuroblastoma, and primitive peripheral neuroectodermal tumor were NSE positive. While Vim was negative; the specificity of the anti-NSE antiserum was poor and other MSRCTs could react with it. Ewing’s sarcoma Vim is positive and in some cases it is NSE positive. Undifferentiated synovial sarcoma Vim positive; in some cases Ker and (or) EMA positive, may have false negative. LCA is a lymphoma specific marker. α_1-ACT has no value in the differential diagnosis of MSRCT.