我院收治了重症肺原性心脏病在急性加重期合并上消化道出血患者３１例，现将其发病机理及预防措施探讨如下。１发病机理１．１缺氧与二氧化碳潴留缺氧能使胃粘膜细胞代谢出现严重障碍，胃粘膜屏障受损，使Ｈ＋－Ｎａ＋离子逆扩散，导致胃粘膜糜烂，发生应激性溃疡出血。二... Our hospital admitted to the severe pulmonary heart disease in acute exacerbation of patients with upper gastrointestinal bleeding in 31 cases, and now its pathogenesis and preventive measures are discussed below. 1 pathogenesis 1.1 hypoxia and carbon dioxide retention Hypoxia can make gastric mucosal cell metabolism a serious obstacle, impaired gastric mucosal barrier, the reverse diffusion of H + -Na + ions, leading to gastric mucosal erosion, the occurrence of stress ulcer bleeding. two...