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Objective To detect methylation status of the 5’ CpG island locating in the promoter region of p27 gene in gastric carcinoma and to analyze the relationship between the aberrant methylation of p27 gene and the bionomics of gastric carcinoma. Methods Methylation-specific PCR were used to detect the methylation status of p27 in gastric carcinoma( n = 49) ,adjacent tissue of carcinoma ( n = 20) and normal tissue
Objective To detect methylation status of the 5 ’CpG island locating in the promoter region of p27 gene in gastric carcinoma and to analyze the relationship between the aberrant methylation of p27 gene and the bionomics of gastric carcinoma. Methods Methylation-specific PCR were used to detect the methylation status of p27 in gastric carcinoma (n = 49), adjacent tissue of carcinoma (n = 20) and normal tissue