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为了解关口村村民乙型肝炎病毒 (HBV)的感染程度 ,对全村 5 2 4人采血进行普查。结果显示 :HBV感染率和乙肝病毒表面抗原 (HBsAg)阳性率平均为 5 7 2 5 %和 12 2 1% ,均随年龄增长而增加。男性分别为 6 4 0 6 %和19 14 % ,女性分别为 5 0 75 %和 5 6 0 % ,且女性HBsAg阳性者中HBeAg阳性占 2 0 0 0 %。HBsAg阳性率 1～ 3岁为 5 4 1% ,<2 0岁平均为 8 10 % ,≥ 2 0岁平均为 15 88%。表明该村HBV免疫水平较低 ,为HBV高感染区 ,男性高于女性 ,感染主要发生在成人。提示该村HBV感染除来自母婴传播外 ,水平传播起着很重要作用 ,因此除新生儿接种乙肝疫苗外 ,还应对其他易感人群 ,尤其是 <2 0岁易感人群接种乙肝疫苗。
In order to understand the degree of infection of hepatitis B virus (HBV) in Guankou village, 542 blood samples were collected from the whole village. The results showed that the positive rates of HBV infection and HBsAg were 5752% and 1221%, both increased with the increase of age. Men were respectively 66.0% and 19.14%, women were respectively 75.5% and 56.0%, and women with HBsAg positive were HBeAg-positive 20%. The positive rate of HBsAg was 51 41% at 1 ~ 3 years, 810% at <20 years and 15 88% at 20 years. This indicates that the village has a low level of HBV immunity, which is a high HBV infection area. The male is higher than the female, and the infection mainly occurs in the adult. It is suggested that HBV infection in this village should play a very important role in transmitting HBV beyond mother-to-child transmission. Therefore, in addition to new-born hepatitis B vaccination, hepatitis B vaccine should be administered to other susceptible populations, especially those <20 years old.