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[目的]探讨老年与中青年胃癌不同的临床特征。[方法]回顾性分析2005年1月～2009年12月新收治的3009例胃癌患者资料,按照年龄分为老年组(≥60岁)和中青年组(﹤60岁)。[结果]老年组患者1835例(60.98%),中青年组患者1174例(39.01%);胃癌患者男女比例为1︰0.28,老年组中男性比例79.3%高于中青年中男性比例75.2%(χ2=7.066,P=0.008);胃癌患者汉族:维吾尔族:哈萨克族比例为13.8︰4.5︰1,老年组中民族构成比与中青年中民族构成比分布之间的差异无统计学意义(χ2=0.269,P=0.992);病变在胃体者占49.4%,其次为胃窦胃角占23.6%,贲门(食管胃交接处)胃底占13.4%,涉及多部位者占12.5%,残胃者占1.2%;病理类型构成比大小顺序为低分化腺癌45.7%、中分化腺癌31.4%、黏液腺癌12.9%、高分化腺癌8.5%、印戒细胞癌1.6%。[结论]老年组胃癌与中青年组的临床特征有所不同,在临床上应采取相适应的诊疗措施。
[Objective] To explore the different clinical features of gastric cancer in elderly and middle-aged patients. [Methods] The data of 3009 cases of newly diagnosed gastric cancer admitted from January 2005 to December 2009 were retrospectively analyzed. They were divided into the elderly group (≥60 years old) and the middle-aged young group (≤60 years old) according to the age. [Results] There were 1835 (60.98%) patients in the elderly group and 1174 (39.01%) patients in the middle-aged and young group. The ratio of male to female patients was 1︰0.28 in gastric cancer patients, 79.3% in elderly patients and 75.2% (χ2 = 7.066, P = 0.008). There was no significant difference between Han nationality in Han nationality and Uygur nationality: Kazak ethnicity was 13.8︰4.5︰1 in the elderly group (χ2 = 7.066, P = 0.008) = 0.269, P = 0.992). Lesions in the corpus accounted for 49.4%, followed by gastric antrum in 23.6%, gastric cardia (esophagogastric junction) in 13.4% of the stomach, mucosal involvement in 12.5% Accounting for 1.2%. The order of the pathological types was 45.7% for poorly differentiated adenocarcinoma, 31.4% for moderately differentiated adenocarcinoma, 12.9% for mucinous adenocarcinoma, 8.5% for well-differentiated adenocarcinoma, and 1.6% for signet-ring cell carcinoma. [Conclusion] The clinical features of gastric cancer in young group are different from those in young and middle-aged group. Clinically, appropriate clinical measures should be taken.