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目的观察电针联合选择性雌激素受体调节剂(替勃龙)治疗绝经期情感障碍的疗效。方法将已绝经并伴有情感障碍的患者40例按就诊顺序随机分为2组,每组20例。电针联合替勃龙治疗组:电针,4次/周,替勃龙(每片2.5 mg)1片/隔日。单纯替勃龙对照组:替勃龙(每片2.5mg)1片/隔日。治疗周期为4周。治疗前和治疗后各评价1次,应用汉密尔顿抑郁量表(HAMD)评价抑郁程度。结果本组临床观察显示治疗组与对照组治疗后HAMD评分比较差异有显著性(P<0.05),2组之间总有效率差异有显著性(P<0.05)。结论电针联合替勃龙治疗绝经期情感障明显优于单纯替勃龙。
Objective To observe the therapeutic effect of electroacupuncture combined with selective estrogen receptor modulators (tibolone) on menopausal affective disorder. Methods Forty patients with postmenopausal and affective disorders were randomly divided into two groups (n = 20 in each group). Electroacupuncture combined tibolone treatment group: electroacupuncture, 4 times / week, tibolone (2.5 mg per tablet) 1 / every other day. Pure tibolone control group: tibolone (each 2.5mg) 1 / every other day. The treatment cycle is 4 weeks. Before treatment and after treatment, each evaluation 1, the use of Hamilton Depression Scale (HAMD) evaluation of depression. Results The clinical observation showed that the HAMD score of the treatment group and the control group were significantly different (P <0.05), and the total effective rate was significantly different between the two groups (P <0.05). Conclusion Electroacupuncture combined with tibolone treatment of menopausal symptoms is significantly better than pure tibolone.