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目的 观察急诊电子预检分诊系统对急性心肌梗死(acute myocardial infarction,AMI)患者经皮冠脉介入治疗(percutaneous coronary intervention,PCI)术后继发心肌缺血性再灌注损伤的影响.方法 选取2015年12月-2016年12月中国人民解放军海军总医院行急诊PCI的AMI患者64例,根据是否经急诊电子预检分诊系统干预随机分为干预组和对照组(n=32),检测术前、术后外周血中白介素-1(interleukin-1, IL-1)、IL-6、IL-10、肿瘤坏死因子(tumor necrosis factor alpha,TNF-α)的含量和中性粒细胞(polymorphonuclearneutrophils,PMNs)凋亡率;分别测定血浆丙二醛(malondialdehyde,MDA)含量;应用校正TIMI帧数评价左心射血分数(left ventricular ejection fraction, LVEF)和血流介导的血管扩张功能(flow mediated dilation,FMD),计算分诊正确率.结果 PCI术前,两组的IL-1、IL-6、IL-10、TNF-α和MDA差异无统计学意义(P＞0.05),PCI术后,与对照组比,干预组IL-1、IL-6、TNF-α和MDA浓度降低(P<0.05),IL-10浓度升高(P<0.05).PCI术中,与对照组比,干预组术中的LVEF、FMD和分诊正确率明显增高(P<0.05),PCI术后,与对照组比,干预组PMNs凋亡率增高(P<0.05).结论 AMI患者PCI术前和术后应用急诊电子预检分诊系统可显著减轻或改善AMI相关的炎性及心功能损伤.“,”Objective To observe the effects of emergency electronic pre-examination system on acute myocardial infarction (AMI) patients with myocardial ischemic reperfusion injury after percutaneous coronary intervention (PCI). Methods From December 2015 to December 2016 were 64 cases with AMI patients underwent emergency PCI is divided into according to emergency electronic preview triage system intervention again randomly to separate 2 group (32 cases in each group). The plasma interleukin-1(IL-1), interleukin-6(IL-6), interleukin-10(IL-10), tumor necrosis factor alpha(TNF-α), malondialdehyde (MDA), and the apoptosis rate of polymorphonuclearneutrophils(PMNs) were detected before and after surgery. The left ventricular ejection fraction(LVEF), flow mediated dilation(FMD) and diagnostic accuracy rate were observed and compared . Results Before PCI, the levels of IL-1, IL-6, IL-10, TNF-α and MDA in 2 groups had no differences (P＞0.05). Compared with the control group, IL-1, IL-6, TNF-α and MDA had decreased (P<0.05) and IL-10 had increased (P<0.05). In PCI, compared with the control group, the LVEF, FMD and diagnostic accuracy rate in the intervention group was significantly higher (P<0.05). After PCI, compared with the control group, the apoptosis rate of PMNs in the intervention group was higher(P<0.05). Conclusions The application of emergency electronic pre-triage system in patients with AMI before PCI and after PCI can significantly reduce or improve AMI-related inflammatory and cardiac dysfunction.