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[石棉引起的疾患] 1.石棉肺:石棉尘系一种纤维性粉尘,进入肺内可逐渐形成广泛而严重的纤维化病变,有关它的发病原理迄今仍未阐述清楚。曾有人用Allison氏的矽肺发病二期理论加以解释,然而二者的发病机理并不相同。目前的研究主要是从石棉尘理化性质(包括形态,直径大小);吞噬细胞反应;免疫学等方面进行研究。已知石棉尘的靶细胞为巨噬细胞、肺泡上皮细胞、间皮细胞、纤维母细胞,又知各种类型的石棉其致纤维性有一定差异:铁石棉(Amesite)青石棉(Crocidolite)比温石棉
[Asbestos-induced disorders] 1. Asbestos lung: Asbestos dust is a fibrous dust that enters the lungs and may gradually form extensive and severe fibrosis. The pathogenesis of it has not been elucidated so far. Allison’s second stage theory of silicosis has been used to explain, however, the pathogenesis of both is not the same. The current research is mainly from the physical and chemical properties of asbestos dust (including morphology, diameter); phagocyte response; immunology and other aspects of research. Known asbestos dust target cells macrophages, alveolar epithelial cells, mesothelial cells, fibroblasts, also known as various types of asbestos fibroblasts have some differences: Amesite crocidolite (Crocidolite) than Chrysotile