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最近,腺苷酸活化蛋白激酶(adenosine mono-phosphate-activated protein kinase,AMPK)已经成为调节血管平滑肌收缩的新的靶点。该研究探讨α硫辛酸(α-lipoic acid,α-LA)对Wistar-Kyoto(WKY)大鼠与自发性高血压大鼠(spontaneously hypertensive rats,SHR)主动脉环的血管舒张作用和可能的机制。方
Recently, adenosine mono-phosphate-activated protein kinase (AMPK) has become a new target of regulating the contraction of vascular smooth muscle. This study was aimed to investigate the vasodilatation and possible mechanism of α-lipoic acid (α-LA) on the aortic rings of Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR) . square