胎粪吸入综合征(Meconium Aspiration Syndrome,MAS)常发生于足月儿或过期产儿,是胎儿在分娩过程中由于将有胎粪污染的羊水吸入呼吸道而引起。有胎粪吸入的新生儿在出生2～3日内可发展为进行性呼吸衰竭,严重缺氧,甚至死亡。是新生儿主要死亡原因之一。病死率高达28％。在足月儿其病死率是所有其他死亡原因总和的20倍。由此可见其后果严重。近年来新生儿呼吸道疾病的治疗方法已有很大改进如通气与加压给氧治疗等。但对胎粪吸入综合征,除了支持疗法与对症疗法外,其治疗效果还不够理想。因此 Meconium aspiration syndrome (Meconium Aspiration Syndrome, MAS) often occurs in term infants or expired children, is the fetus in the delivery process due to amniotic fluid contaminated amniotic fluid inhalation into the respiratory tract caused. Neonates with meconium aspiration may develop progressive respiratory failure within 2-3 days of birth, severe hypoxia, and even death. One of the major causes of death in newborns. Case fatality rate as high as 28%. At term, its case fatality rate is 20 times the sum of all other causes of death. This shows that the consequences are serious. In recent years, neonatal respiratory disease treatment has been greatly improved, such as ventilation and pressurized oxygen therapy. However, meconium aspiration syndrome, in addition to supportive therapy and symptomatic therapy, the treatment effect is not satisfactory. therefore