【摘 要】
:
目的 观察静脉注射地佐辛联合罗哌卡因术毕切口浸润在腹腔镜卵巢囊肿切除术后镇痛中的效果.方法 选取内蒙古医科大学附属医院2014年9月至2015年3月全身麻醉下行腹腔镜卵巢囊
【机 构】
:
内蒙古医科大学附属医院麻醉科, 呼和浩特,010030
论文部分内容阅读
目的 观察静脉注射地佐辛联合罗哌卡因术毕切口浸润在腹腔镜卵巢囊肿切除术后镇痛中的效果.方法 选取内蒙古医科大学附属医院2014年9月至2015年3月全身麻醉下行腹腔镜卵巢囊肿切除手术的患者60例,完全随机分为空白对照组、地佐辛组、地佐辛联合罗哌卡因组,各20例.空白对照组不做任何处理,地佐辛组患者于术毕前30 min静脉注射地佐辛0.1 mg/kg,地佐辛联合罗哌卡因组患者于术毕前30 min静脉注射地佐辛0.1 mg/kg,在关气腹后以0.5%罗哌卡因在皮下组织与壁层腹膜内逐次浸润,每个切口2~3ml.3组麻醉诱导、维持方法相同,术中根据脑电双频指数调整静脉麻醉深度,在麻醉清醒后的0、2、4、6、12、24h记录疼痛视觉模拟量表(VAS)评分,若>4分则给予哌替啶1 mg/kg肌内注射,并记录使用镇痛剂的例数及术后不良反应发生情况,术中持续监测无创血压、心电图、呼吸、脉搏、血氧饱和度.结果 地佐辛联合罗哌卡因组术后4、6、12 h镇痛效果优于空白对照组及地佐辛组,差异有统计学意义[4 h:(1.7±0.9)分比(3.5±0.8)、(3.1±0.5)分,6h:(1.8±0.7)分比(3.6±1.0)、(2.0±0.8)分,12 h:(1.6±0.8)分比(3.0±1.0)、(2.9±0.8)分,P<0.05或P<0.01].地佐辛组术后4、6h镇痛效果优于空白对照组,差异有统计学意义(P<0.05).地佐辛联合罗哌卡因组额外镇痛药使用率低于空白对照组与地佐辛组[10.0% (2/20)比65.0% (13/20)、30.0% (6/20),P<0.05].3组均无呼吸抑制情况发生,恶心、呕吐发生率差异均无统计学意义(均P>0.05).3组术后平均动脉压、心率比较差异无统计学意义(P>0.05).结论 静脉注射地佐辛联合罗哌卡因术毕切口浸润在腹腔镜卵巢囊肿切除术后镇痛效果明确、不良反应少、安全可行.
其他文献
AIM: To compare, in a pig liver transplantation model,the protective effect of UW with that of IGL-1, a highsodium preservation solution containing polyethylene
AIM: To investigate the protein and mRNA expression of semaphorin 6D in gastric carcinoma and its significance.METHODS: The protein and mRNA expression of semap
AIM: To investigate the association between malnutrition and quality of life in patients with benign gastrointestinal disease. METHODS: Two hundred patients (10
AIM: To evaluate the effect of relaxing music during colonoscopy under low-dose conscious sedation, on patient satisfaction, scope insertion time and procedure
AIM: To explore rectal nitric oxide (NO) as biomarker of treatment response in ulcerative colitis (UC) and Crohn's disease (CD), and examine relationships betwe
Background Advances in treatment have greatly reduced the risk of blindness from this disease, but because diabetes is so common, diabetic retinopathy remains a
AIM: To compare gene expression profiles of pancreatic adenocarcinoma tissue specimens, human pancreatic and colon adenocarcinoma and leukemia cell lines and no
In this case report we describe for the first time an association between autoimmune hepatitis (AIH) and uveitis, without any doubts about other possible etiolo
AIM: To explore the effects of ketamine on hemodynamics, plasma proinflammatory cytokine (TNF-α and IL-6) levels and nuclear factor kappa B (NF-κB) activation
AIM: To evaluate the role of azathioprine (AZA) in Indian patients with ulcerative colitis over longer duration of time. METHODS: One hundred f ifty six patient