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Objective: To evaluate the effects and adverse reactions of Boeing capsules plus FOLFOX4 regimen in clinical treatment for colon carcinoma. Methods: Total patients with colon carcinoma were randomly divided into two groups from January 2005 to May 2006: group A (45 patients) were received Boeing capsules plus FOLFOX4 regimen treatment, and group B (49 patients) were received FOLFOX4 regimen treatment only. Results: Boeing capsules could obviously improve the life quality of the colon carcinoma patients. The weight gain in group A was higher than that of group B. No significant existed in the body immune function changes (T cell subgroup). But it could ameliorate the adverse reactions which induced by the chemotherapy. Conclusion: Boeing capsules can improve the life quality of the colon carcinoma patients and ameliorate the symptoms and sign which induced by the chemotherapy.