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目的探讨早期内镜下鼻胆引流术(ENBD)在急性重症胆源性胰腺炎治疗中的价值与安全性。方法将26例早期内镜下行ENBD治疗与30例内科保守治疗的临床资料作对照,进行实验室检查、CT评分以及临床腹痛缓解时间、住院天数、并发症发生率及死亡率等指标对比分析。结果 ENBD组住院第7d血淀粉酶、总胆红素下降幅度显著大于保守治疗组(P<0.05);ENBD组的死亡率、平均住院时间及腹痛持续时间与对照组比较差异有显著性(P<0.05)。结论早期内镜下ENBD对急性重症胆源性胰腺炎是安全、有效的治疗措施。
Objective To investigate the value and safety of early endoscopic nasobiliary drainage (ENBD) in the treatment of acute severe biliary pancreatitis. Methods The clinical data of 26 cases with early endoscopic descending ENBD and 30 cases of conservative medical treatment were compared. The laboratory tests, CT scores and clinical abdominal pain relief time, hospitalization days, complication rates and mortality were compared and analyzed. Results The decrease of serum amylase and total bilirubin in ENBD group was significantly greater than that in conservative group on the 7th day (P <0.05). The mortality, average length of hospital stay and duration of abdominal pain in ENBD group were significantly different from those in control group (P <0.05). Conclusion Early endoscopic ENBD is a safe and effective treatment for acute severe biliary pancreatitis.