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用间接免疫荧光法检测110例不同病程、病期及病型的流行性出血热病人尿中及血清中特异性抗体。尿中IgM型抗体阳性率为62.7％。尿中IgG型抗体阳性率91.8％与血清IgG型者90.9％相似,而总阳性率(IgG或IgM有一项以上阳性者的总检出率)99.1％则高于血清IgG者。20例其它疾病及10例正常人尿抗体均为阴性。结果表明尿抗体检查法是特异且可靠的,它比血清学方法简便、灵敏、为临床诊断可早期快速得出结果,不用采血有利于病人。IgM型抗体阳性率受病程、病期、病型及尿蛋白量的影响较明显。
Indirect immunofluorescence was used to detect urine and serum specific antibodies in 110 patients with epidemic hemorrhagic fever with different course, stage and type of disease. The positive rate of urinary IgM antibody was 62.7%. The positive rate of IgG antibody in urine was 91.8% similar to that of serum IgG in 90.9%, while the total positive rate (total IgG or IgM positive rate was 99.1%) was higher than that of serum IgG. 20 cases of other diseases and 10 cases of normal human urine antibody were negative. The results show that urine antibody test is specific and reliable, it is more simple and sensitive than serological methods, early diagnosis of clinical results can be obtained quickly, without blood in favor of the patient. The positive rate of IgM antibody is affected by the course of disease, disease period, disease type and urine protein quantity.