自1973年国外报导口服避孕药发生良性腺瘤以来,1977年Klatskin氏曾回顾世界各地的报导;发生肿瘤的病例已大大超过250例以上。但妇女口服避孕药发生肝脏肿瘤的发病率是很低的;国外统计1974年为1.36/百万,到1976年为5.94/百万,似有增加的趋势。本文报告丹麦皇家医学院所属医院1970～1979年期间收治因口服避孕药伴发肝脏肿瘤 Since 1973, foreign reports of oral contraceptives benign adenomas since 1977, Klatskin’s reviewed reports from around the world; the incidence of cancer has greatly exceeded 250 cases. However, the incidence of hepatic tumors in women taking oral contraceptives is very low; foreign statistics show 1.36 per million in 1974 and 5.94 per million in 1976, which seems to be on the rise. This article reports Danish Royal College of Medicine hospital from 1970 to 1979 treated with oral contraceptives associated with liver cancer