乙酰胆碱(Ach)是一重要的神经介质。有实验表明,Ach参与调节动物和人体的GH与ACTH的分泌。近来,有些作者报道迷走神经阻滞剂——阿托品可抑制人体的GH对GHRH的反应,并对以往认为胆碱能神经是在下丘脑水平控制GH分泌的观点提出异议,认为阿托品可能对垂体有非特异性抑制作用。为此,本文作者分别观察了阿托品对下丘脑的4种释放激素(LHRH、TRH、CRH和GHRH)效应的影响。 Acetylcholine (Ach) is an important neurotransmitter. Experiments show that Ach is involved in regulating the secretion of GH and ACTH in animals and humans. Recently, some authors have reported that the vagal blocker, atropine, inhibits the body’s GH response to GHRH and disagrees with the notion that cholinergic nerves control GH secretion at the hypothalamus in the past, arguing that atropine may be non-specific to the pituitary Inhibition. To this end, the authors observed the effects of atropine on the hypothalamic four kinds of releasing hormone (LHRH, TRH, CRH and GHRH) effects.