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背景:加拿大每年接受超过20 万移民。在安大略省的多伦多,移民病例占所有结核病人的92%。为了实施更为有效的结核病规划,需要了解新移民的流行病学特征。设计:本研究以人群为基础,对1990-1997 年安大略地区新移民作回顾性队列分析。计算调整率、危险度比(RRs)、入境后的危险度,通过补充的log-log模型描述结核病的发病率,比较不同性别、年龄组、出生地区下的生存情况,并确定疾病的预报因子。结果:新移民中的结核病发病率比非土著加拿大人高23 倍(95%CI:20.9-25.5)。16-30 岁和>65 岁两个年龄组发病率最高。来自非洲撒哈拉地区的男性和女性人群(RR=95.5,95%CI:84.3-108.2)的结核病发病率最高,其次是印度和亚洲人。入境后危险度降低,但是仍保持较高水平。最高发病率与1990年入境和在加拿大居住时间<1 年这两个因素相关。结论:结核病发病率随着出生地、入境年龄和在加拿大居住时间而异。性别不具显著性。来自非洲撒哈拉地区和年龄>65 岁的人群发病率最高。在入境后的1-2 年内,发病率明显降低,之后进入平台期。
Background: Canada receives over 200,000 immigrants annually. In Toronto, Ontario, immigration accounts for 92% of all TB patients. In order to implement a more effective TB program, it is important to understand the epidemiological characteristics of newcomers. Design: This study, based on population, retrospectively cohort analyzed new arrivals from Ontario in 1990-1997. RRs, post-entry risk were calculated and the incidence of tuberculosis was described by a supplemental log-log model to compare survival under different sexes, age groups and birth regions and to determine the predictor of disease . Results: The incidence of tuberculosis among newcomers was 23 times higher (95% CI: 20.9-25.5) than non-indigenous Canadians. The highest incidence was found in both age groups of 16-30 years and> 65 years. Male and female populations from sub-Saharan Africa (RR = 95.5, 95% CI: 84.3-108.2) had the highest incidence of tuberculosis, followed by India and Asia. After the arrival of the risk reduction, but still maintain a high level. The highest incidence was related to the two factors, immigration in 1990 and residence in Canada <1 year. Conclusion: The incidence of tuberculosis varies according to place of birth, age of entry, and length of stay in Canada. Sex is not significant. The highest prevalence is in the sub-Saharan African region and people over the age of 65. Within 1-2 years after entry, the incidence rate was significantly reduced, then entered the platform period.